BPC-157 Canada | Research Guide
28 Jun 2026BPC-157 Canada | Research Guide
Canada Research Guide Research Use Only Updated September 2026
BPC-157 Canada Research Guide
BPC-157 is the most widely requested recovery research peptide in Canada. This guide covers what BPC-157 is, its published research profile across cytoprotective and tissue-repair models, why purity documentation matters, how it compares to related recovery compounds, and what Canadian researchers should evaluate when selecting a supplier.
Direct Answer: BPC-157 (Body Protection Compound-157) is a synthetic 15-amino-acid pentadecapeptide derived from a protective protein found in human gastric juice. It has been studied in over 100 published non-clinical investigations for cytoprotective, tissue-repair, and anti-inflammatory signaling properties. CAS Number: 137525-51-0. In Canada, ThePeptide.ca supplies the 10 mg research vial at $59.99 CAD with free, tracked Canada-wide shipping and no minimum order. The current lot, BPC10-0626-01, was verified at 99.64% purity by HPLC-UV at 214 nm by Testides (Toronto), with identity confirmed by mass spectrometry.
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What Is BPC-157?
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide consisting of 15 amino acids. It is a partial sequence of a body protection compound (BPC) that was first isolated from human gastric juice. Unlike many synthetic peptides, BPC-157 is notable for its stability in gastric conditions, which is unusual for peptides of its size and has contributed to sustained research interest.
The compound has been studied in non-clinical models for over two decades, with published investigations spanning gastrointestinal cytoprotection, musculoskeletal tissue repair, vascular function, and neurological signaling pathways. It remains one of the most requested research peptides in Canada.
| Property | Detail |
|---|---|
| Compound Name | BPC-157 (Body Protection Compound-157) |
| Molecular Class | Synthetic pentadecapeptide |
| Amino Acid Length | 15 amino acids |
| Origin | Derived from gastric juice body protection compound |
| CAS Number | 137525-51-0 |
| Research Format | Lyophilized powder, 10 mg vial |
| Price | $59.99 CAD (10 mg, SKU BPC-10MG) — free tracked Canada-wide shipping, no minimum order |
| Key Feature | Gastric stability unusual for peptides of this class |
| Use Context | Laboratory and non-clinical research only |
BPC-157 Research Profile and Mechanisms
BPC-157 research spans multiple biological systems. The compound has been investigated for activity in the following non-clinical research areas:
| Research Area | Investigated Mechanism | Key Pathways |
|---|---|---|
| Gastrointestinal cytoprotection | Gastric mucosal integrity, ulcer models | NO system, prostaglandin modulation |
| Musculoskeletal tissue | Tendon, ligament, and muscle repair models | VEGF, EGF, FAK-paxillin signaling |
| Vascular function | Angiogenesis, blood vessel formation | VEGF pathway, nitric oxide system |
| Neuroprotective research | Central nervous system injury models | CNS signaling pathways |
| Anti-inflammatory models | Inflammatory response modulation | Cytokine signaling, NO pathway |
The breadth of published research is notable — BPC-157 appears in over 100 published studies, which is exceptionally high for a synthetic research peptide. This research density makes it a compound of significant interest for investigators working across multiple biological systems.
Key Published Studies
The following peer-reviewed publications represent landmark research in the BPC-157 literature. Each is indexed in PubMed with a unique PMID for verification.
| Study | Focus | Key Finding |
|---|---|---|
| Sikiric et al., 1999 (PMID: 17657443) | Cytoprotective profile | Set out the early pharmacological profile of BPC 157, including gastric protection and tissue-repair activity across several organ systems |
| Brcic et al., 2009 (PMID: 20388964) | Angiogenesis in muscle and tendon | Reported enhanced angiogenic response with up-regulated VEGF expression in muscle and tendon healing models, with no direct effect on isolated endothelial cells in culture |
| Seiwerth et al., 2018 (PMID: 29998800) | Review of angiogenic growth-factor pathways | Reviewed BPC 157 alongside standard angiogenic growth factors across gastrointestinal, tendon, ligament, muscle and bone healing models |
| Chang et al., 2011 (PMID: 21030672) | Tendon healing | Examined tendon outgrowth, cell survival and cell migration in tendon-healing models |
| Vukojević et al., 2020 (PMID: 32558293) | Central nervous system model | Examined BPC 157 in a rat model of hippocampal ischemia/reperfusion injury |
| Vasireddi et al., 2025 (PMID: 40756949) | Systematic review of the evidence base | Screened 544 articles published 1993–2024 and included 36; of those, 35 were preclinical and only one was clinical — a direct measure of how little human data exists |
| McGuire et al., 2025 (PMID: 40789979) | Narrative review of proposed mechanisms | Consolidated three decades of laboratory work, describing angiogenesis via VEGFR2 and nitric-oxide modulation through the Akt–eNOS axis as the most frequently examined pathways in models |
Note: All studies are non-clinical research. BPC-157 is not approved for therapeutic use. ThePeptide.ca materials are intended strictly for laboratory research.
Why Purity Matters for BPC-157 Research
Because BPC-157 is widely available from multiple suppliers, quality variation is a significant concern. Researchers should evaluate suppliers based on documentation transparency, not just product availability.
| Quality Signal | Why It Matters |
|---|---|
| Measured HPLC purity, reported to the decimal | Reduces variables and improves consistency across research protocols |
| Mass spectrometry confirmation | Confirms molecular identity matches target compound |
| Batch-specific COA | Links documentation to the specific lot you received |
| Third-party testing | Independent verification removes self-reporting bias |
| Published lab results | Transparent quality evidence accessible before purchase |
The current BPC-157 lot, BPC10-0626-01, was tested by Testides (Toronto) and returned 99.64% purity by HPLC-UV at 214 nm with 10.99 mg of measured content, identity confirmed by mass spectrometry. The Wolverine Blend lot HEAL-0626-01 returned 98.64% combined on the same method — a blend is assayed as a single sample, so its figure is combined and sits lower by arithmetic rather than by quality. Neither Testides nor Janoshik Analytical is accredited to ISO/IEC 17025. View current lab results →
Storage and Handling for BPC-157
BPC-157 is notable for its relative gastric stability compared to other peptides of similar size. However, proper storage remains essential for research consistency.
| Condition | Recommendation |
|---|---|
| Lyophilized (unopened) | Store at -20°C for long-term; 2-8°C for short-term |
| Light exposure | Protect from direct light |
| Freeze-thaw | Minimize cycles — aliquot for multiple uses |
This guide covers sealed-vial storage only. It contains no dosing, administration, route, reconstitution or preparation information, and none is available on request.
Why Canadian Researchers Choose Domestic BPC-157 Suppliers
- No customs delays or seizure risk — Domestic shipping avoids border inspections entirely
- Faster delivery — ThePeptide.ca ships from British Columbia with tracked delivery Canada-wide, free on every order with no minimum — orders are dispatched within 48 hours Monday to Friday
- Temperature control — Shorter transit reduces temperature fluctuation exposure
- Canadian dollar pricing — $59.99 CAD for the 10 mg vial, with no exchange rate markup or hidden conversion fees
- Volume pricing — automatic at checkout with no code: 10% off at 3 or more units, 15% at 5 or more, 20% at 10 or more, across all products with no exclusions
- Local support — Canadian customer service at info@thepeptide.ca
Source BPC-157 from a Trusted Canadian Supplier
BPC-157 10mg — $59.99 CAD Wolverine Blend 10mg — $95.00 CADBPC-157 vs Related Recovery Compounds
| Feature | BPC-157 | TB-500 (Thymosin Beta-4) | Wolverine Blend |
|---|---|---|---|
| Peptide class | Pentadecapeptide (15 aa) | 43-amino-acid peptide | BPC-157 + TB-500 combined |
| Primary mechanism | NO pathway, VEGF/EGF signaling | Actin sequestration, cell migration | Dual-pathway activation |
| Research focus | Cytoprotection, GI, musculoskeletal | Wound healing, cardiac tissue | Combined recovery models |
| Gastric stability | Unusually stable | Standard peptide stability | Blend-dependent |
| Published studies | 100+ non-clinical | Extensive thymosin literature | Emerging combination data |
| Price (CAD) | 10 mg — $59.99 | Available in the blend | 10 mg — $95.00 |
A side-by-side breakdown of the two mechanisms is in our BPC-157 vs TB-500 comparison. Researchers studying combined recovery pathways can explore our Wolverine Blend (BPC-157 + TB-500) →
Frequently Asked Questions
How much does BPC-157 cost in Canada?
What is BPC-157 used for in research?
Is BPC-157 legal to purchase in Canada?
What makes BPC-157 different from other recovery peptides?
What purity should I look for when buying BPC-157 in Canada?
How should BPC-157 be stored?
Does ThePeptide.ca ship BPC-157 across Canada?
Related Research Resources
References
- Sikiric P, et al. The pharmacological properties of the novel peptide BPC 157 (PL-10). Inflammopharmacology. 1999;7(1):1-14. PubMed: 17657443
- Brcic L, Brcic I, Staresinic M, Novinscak T, Sikiric P, Seiwerth S. Modulatory effect of gastric pentadecapeptide BPC 157 on angiogenesis in muscle and tendon healing. Journal of Physiology and Pharmacology. 2009;60 Suppl 7:191-196. PubMed: 20388964
- Seiwerth S, et al. BPC 157 and standard angiogenic growth factors. Gastrointestinal tract healing, lessons from tendon, ligament, muscle and bone healing. Current Pharmaceutical Design. 2018;24(18):1972-1989. PubMed: 29998800
- Chang CH, et al. The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. Journal of Applied Physiology. 2011;110(3):774-780. PubMed: 21030672
- Vukojević J, et al. The effect of pentadecapeptide BPC 157 on hippocampal ischemia/reperfusion injuries in rats. Brain and Behavior. 2020;10(8):e01726. PubMed: 32558293
- Vasireddi N, et al. Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review. HSS Journal. 2025. PubMed: 40756949
- McGuire C, et al. Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing. Current Reviews in Musculoskeletal Medicine. 2025. PubMed: 40789979
For laboratory and research use only. The information on this page is provided for educational and research-context purposes. ThePeptide.ca materials are not represented as approved for human use, veterinary use, or therapeutic application.
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Every lot carries a published, batch-specific lab report, dispatched within 48 hours from BC with free tracked shipping Canada-wide and no minimum: BPC-157 10mg — $59.99 CAD. Browse the full collection →