MOTS-C 10mg
Mitochondrial-Derived Peptide
Compound Overview
MOTS-C is a 16-amino-acid mitochondrial-derived peptide (MDP) encoded within the 12S rRNA region of mitochondrial DNA. It has been extensively studied as a regulator of metabolic homeostasis, cellular energy balance, and exercise capacity, acting primarily through activation of the AMPK pathway. This 10mg research-grade vial provides lyophilized MOTS-C independently verified at 99.025% purity by Janoshik Analytical.
Unlike the incretin class, MOTS-C acts from inside the mitochondrion rather than at a cell-surface receptor — which is why researchers most often study it alongside metabolic work rather than treat it as an alternative to a GLP-1 compound.
Lab results: View current batch COA
Specifications
| Compound | MOTS-C (mitochondrial ORF of the 12S rRNA type-c) |
| Compound class | Mitochondrial-derived peptide (16 amino acids) |
| CAS number | 1627580-64-6 |
| Molecular formula | C101H152N28O22S2 |
| Molecular weight | 2,174.62 g/mol |
| Sequence | Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg (MRWQEMGYIFYPRKLR) |
| Vial contents | 10 mg lyophilized powder |
| Verified purity | 99.025% (HPLC-UV) |
| Testing laboratory | Janoshik Analytical |
| Test methods | HPLC-UV purity + mass spectrometry identity confirmation |
| Storage | Sealed vial: -20°C long-term, 2-8°C short-term. Protect from light. |
| Research applications | Mitochondrial function, AMPK signalling, insulin sensitivity, glucose metabolism, exercise capacity, age-related metabolic decline |
| Key reference | Lee et al., Cell Metabolism, 2015 (PMID: 25738459) |
| Related compounds | GHK-Cu (longevity), Semaglutide (metabolic) |
| Ships from | British Columbia, Canada |
| Intended use | In-vitro laboratory research only |
Research Context & Mechanism+
MOTS-C translocates to the nucleus under metabolic stress and regulates AMPK-dependent gene expression governing glucose utilization, insulin sensitivity, and fatty-acid metabolism. Foundational research includes Lee et al. (Cell Metabolism, 2015, PMID: 25738459) characterizing MOTS-C as a regulator of insulin sensitivity and metabolic homeostasis, and Reynolds et al. (Nature Communications, 2021, PMID: 33397889) demonstrating exercise-induced MOTS-C expression and its role in physical capacity and healthspan.
Researchers commonly study MOTS-C alongside other metabolic compounds such as the GLP-1 class and longevity peptides like GHK-Cu.
Purity & Third-Party Testing+
Every batch is independently tested before release. The current lot was assayed by Janoshik Analytical at 99.025% purity by HPLC-UV, with mass spectrometry identity confirmation. View current batch COA →
Storage & Handling+
Sealed vial: -20°C long-term, 2-8°C short-term. Protect from light. Keep in the original packaging until it reaches the laboratory.
How does shipping work in Canada, and is it free?+
Shipping is free on every order, Canada-wide, with no minimum order value, and every parcel is tracked. All orders ship from British Columbia, Canada.
- Processing: Dispatched within 48 hours (Mon-Fri)
- Delivery: Typically 2-8 business days anywhere in Canada
- Tracking: A tracking number is emailed as soon as your order ships
All research compounds are packaged in temperature-stable, tamper-evident materials. Vials are individually wrapped in discreet, unbranded packaging.
Returns & Refunds+
Damaged orders: info@thepeptide.ca within 48 hours with order number and photos. Sealed, unopened vials eligible for exchange within 14 days. Full refund policy →
For laboratory and research use only. Not for human consumption, veterinary use, or therapeutic application. Not approved by Health Canada. We do not provide preparation, dilution or administration guidance for any compound we sell.
- Sealed vial: −20°C, 24+ months.
- Protect from light and heat.
- Keep in original packaging until use in the laboratory.
- CAS: 1627580-64-6
- Molecular formula: C101H152N28O22S2
- Molecular weight: 2,174.62 g/mol
- Sequence: MRWQEMGYIFYPRKLR (16 amino acids)
- Class: Mitochondrial-derived peptide
- Purity: 99.025% (HPLC)
Not for human or animal use. We do not publish preparation, dilution or usage guidance of any kind.
By purchasing, you confirm research intent and accept full responsibility for compliance.
Mix any research peptides 10 mg or larger — the discount counts your whole order, not one product.
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